Originally Posted by pondering_it_all
A bit of encouraging news: Seems like NAC (n-acetylcystein) might be useful for treating very sick Covid-19 patients in the ICU. This is not an antiviral, it's an antioxidant and a pretty sophisticated clot-buster. The biochemistry is pretty complex. If you are into that stuff, you can watch Medcram #69 on Youtube for the pathways and tons of journal paper references.

Basically, Covid-19 makes a nasty critter called super-oxide which can cause endothelial disruption. Cells in your blood vessel walls that are normally covered by endothelium then release something called VWF. That forms long polymer chains that help bind platelets into clots. The clots are what causes most Covid-19 deaths.

NAC can help reduce super-oxide to OH- and water, and it can break up VWF polymers. In fact, some of those papers actually talk about using NAC to bust clots from other pathologies. This is not very helpful during the virus replication phase. It does nothing to slow that down. But it's nice if doctors have a drug that they can use for critical patients besides heparin. There is a clinical trial underway that uses NAC in exactly this way. Oh, and adverse reactions are so far rare or non-existent.

Yes, NAC is a very interesting drug.

I started today the Eastern Virgina Medical School protocol that you diffused here, for me and for my wife (got the tablets and capsules from Amazon), and I sent the information to my son, my daughter, and my brothers and sisters. Thanks for that very helpful protocol.

By the way, I don't know in what thread you posted the link to the protocol. Would you repost here? It belongs here.

Last edited by GreatNewsTonight; 05/12/20 12:56 AM.

Please take COVID-19 seriously; don't panic but don't deny it; practice social distancing (stay 6ft from people); wash your hands a lot, don't touch your face, don't gather with too many people, so that you help us contain it.