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Joined: May 2006
Posts: 5,026 Likes: 98
old hand
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OP
old hand
Joined: May 2006
Posts: 5,026 Likes: 98 |
I think you are probably right about the vaccine. My problem with it is that they may skip some steps to be first in line for sales. I also suspect China is the one in the lead right now. Not only that but they have said they will share it with the world. I can only assume that, before that happens, China will have had a couple million folks using that vaccine and records are kept. I also notice that the Oxford University vaccine is back at it and testing is in phase 2/3. I guess they must have 'adjusted' it so that it worked.
Anyway..............
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Joined: Feb 2006
Posts: 12,129 Likes: 257
Pooh-Bah
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Pooh-Bah
Joined: Feb 2006
Posts: 12,129 Likes: 257 |
I don't think Oxford has made any changes. They are just hoping it works in humans but not in monkeys. Which is not a good bet, because another group in the US already published their results and two of their vaccines worked great in monkeys. That study included challenging the vaccinated monkeys with live virus and it worked perfectly.
Educating anyone benefits everyone.
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Joined: Feb 2006
Posts: 12,129 Likes: 257
Pooh-Bah
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Pooh-Bah
Joined: Feb 2006
Posts: 12,129 Likes: 257 |
Rather a big scandal regarding the Lancet HCQ paper: Looks like they faked a lot of data. ALL their data comes from a proprietary company one of the co-authors owns, and they won't let anybody look at it. They claim it includes case data from up until just a few days before the paper was submitted from over 600 hospitals, many of whom have never heard of this company. Extracting patient data from hospitals to combine is difficult, takes months, has to pass ethics boards, etc.
Then they claim out of those many thousands of patient records they matched patients into groups with 23 different matching parameters. (Like sex, smoker, diabetes, etc.) Collecting all that data would have taken months and had many people doing it. The paper only mentions four co-authors, none of them epidemiologists or statisticians.
Lancet is trying to get "some clarification" from the authors, as they put it. Lancet is going to wind up with a very damaged reputation from this. Meanwhile WHO has stopped all HCQ trials, Fauci has jumped on board, several countries have forbidden HCQ use for Covid-19 because of this paper.
Educating anyone benefits everyone.
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Joined: Mar 2003
Posts: 8,080 Likes: 134
veteran
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veteran
Joined: Mar 2003
Posts: 8,080 Likes: 134 |
If there is a problem, it is precisely this kind of thing which taints all serious scientific studies. Conservatives already believe scientists are the servants of satan and of course are deeply involved in the global conspiracy to enslave the poor abused conservative.
Scientists have to do better.
ignorance is the enemy without equality there is no liberty Save America - Lock Trump Up!!!!
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Joined: Feb 2006
Posts: 12,129 Likes: 257
Pooh-Bah
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Pooh-Bah
Joined: Feb 2006
Posts: 12,129 Likes: 257 |
The politicization of hydroxychloroquine may be moot: East Virginia Medical School has added quercetin to their treatment protocol, even at the prophylactic stage. Quercetin is a zinc ionophore, like hydroxychloroquine but without the QT elongation some doctors worry about. I am actually taking it, since it is available over-the-counter. It is actually a flavonoid present (in lower amounts) in a lot of vegetables and fruits. They recommend prophylactic Vitamins D3 and C, zinc, and Pepcid or the generic equivalent.
They also want people to take melatonin. I've been taking it for a couple of nights and all I can say is: Damn! This is powerful stuff for supposedly a harmless supplement. I really go right to sleep and stay asleep for 8 hours. But if I have to set the alarm for sunrise to let dogs out, I can still function fine, and then go back to sleep when it's done.
Educating anyone benefits everyone.
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Joined: Feb 2006
Posts: 12,129 Likes: 257
Pooh-Bah
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Pooh-Bah
Joined: Feb 2006
Posts: 12,129 Likes: 257 |
Nice accepted article for the American Journal of Epidemiology: Early Outpatient Treatment The author reviews the literature to find the miniscule number of deaths actually attributed to hydroxychloroquine + azithromycin, compared to the number of Covid-19 patients dying every day. He criticizes the use of antivirals like remdesivir and HCQ for critically ill patients due to scarcity and FDA restrictions. Suggests that we need to concentrate on keeping Covid-19 patients from ever needing hospitalization, and presents the actual reports in which HCQ + AZ have proved to do this very well, including one report in which inclusion of zinc sulphate cut mortality in half. In other words, pretty much the opposite of what the Lancet article suggested. Interesting reading.
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Joined: Sep 2008
Posts: 1,672
member
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member
Joined: Sep 2008
Posts: 1,672 |
Amen, big time, on the melatonin, P-I-A. I have taken one and then realized I couldn't hit the hay for a couple hours, and I didn't feel the least bit drowsy. But in a cozy bed, it works great,
Plus melatonin works like warm milk, and signals your body to release some growth hormone, and that's very healthy.
Just a Missouri school teacher ... stubborn as a mule and addicted to logic.
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Joined: Feb 2006
Posts: 12,129 Likes: 257
Pooh-Bah
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Pooh-Bah
Joined: Feb 2006
Posts: 12,129 Likes: 257 |
I do feel like I could just go back to bed for a few hours when I wake up to pee. I have pretty much just slept for 6.5 hours for years, but with melatonin I can sleep 8 hours. Which might be better for me.
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Joined: Nov 2006
Posts: 19,831 Likes: 180
Carpal Tunnel
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Carpal Tunnel
Joined: Nov 2006
Posts: 19,831 Likes: 180 |
There was a thing going around Facebook that says Covid is not actually a virus but a bacterium and that aspirin or other anticoagulants will prevent or cure it. Links and scientific facts are all provided,
I'll bring it here for your amusement if you'd like to see it.
Good coffee, good weed, and time on my hands...
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Joined: Feb 2006
Posts: 12,129 Likes: 257
Pooh-Bah
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Pooh-Bah
Joined: Feb 2006
Posts: 12,129 Likes: 257 |
Aspirin would not do the job. The seriously ill patients in cytokine storm have so much endothelial inflammation because the virus invades and destroys the lining layer of the blood vessels (where it finds ACE II receptors). This releases von Willebrand factor(VWF) which forms long polymer strands that make for extreme clots. Aspirin is not going to do anything to these VWF strands in your blood stream. It just makes platelets less sticky. Those clots clog up your lung capillaries (looks like ARDS, but isn't), your coronary arteries, your brain arteries, etc. Causing loss of function in all those organs.
NAC (N-acetylcysteine) could help. It contains a sulfur atom that can cleave VWF polymers, and humans tolerate it very well. In that sense, it's kind of an over the counter clot buster! It also helps recharge your glutathione after that protein reduces hydrogen peroxide to water. That makes it a very powerful antioxidant, which reduces the inflammation generated by superoxide and hydrogen peroxide, which are causing the whole mess. The immune cells make these poisons to kill infected cells, but in this case they can make too much and kill us.
Most treatment now anticoagulates with full dose heparin, but some people like EVMS suggest NAC as well.
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