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Joined: Feb 2006
Posts: 12,129 Likes: 257
Pooh-Bah
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Pooh-Bah
Joined: Feb 2006
Posts: 12,129 Likes: 257 |
As I predicted, Lancet paper on HCQ retracted by three of the authors. The fourth author had no comment. He's the owner of the fake company that supplied the data for the paper.
Another paper published by the New England Journal of Medicine: They looked at the ability of HCQ as a post exposure prophylactic. Summary: If you wait four days after the exposure, HCQ does not seem to do much good. There were a few problems. For example, not many of the participants were confirmed to actually have Covid-19 with PCR tests. They also kind of missed the point because zinc was not part of their design, though some of the participants were taking zinc in both control and HCQ arms. Taking zinc was strictly self-reported, so uncontrolled. They also ended up with some very small numbers, so not much of significance could be reported.
They included hospitalizations and death as secondary end points, but halted the study when their primary end point failed. Since the whole idea of an antiviral is to prevent serious illness and hospitalization, it would have been nice if they reported those numbers. So we still don't have confirmation that early HCQ + zinc cuts mortality in half as reported elsewhere.
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Joined: Feb 2006
Posts: 12,129 Likes: 257
Pooh-Bah
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Pooh-Bah
Joined: Feb 2006
Posts: 12,129 Likes: 257 |
BOMBSHELL: The paper that said ivermectin was effective turns out had that same SurgiFake doctor as a coauthor, and his scam company supplied all the data. That paper is going to be retracted, with more black eyes for the journals and possibly innocent co-authors. I think this guy needs to lose his license, if not get a nice new tar and feather suit.
Somebody needs to look through the Citation Index and see what else he has faked.
Educating anyone benefits everyone.
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Joined: May 2006
Posts: 5,026 Likes: 98
old hand
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OP
old hand
Joined: May 2006
Posts: 5,026 Likes: 98 |
it just dawns on me what they are doing (sometimes it takes me longer than others). Anyway, the are doing ALL the tests on their drug AT THE SAME TIME! Right through test 3 (with thousands of testers. I think they are using India for that one). Apparently there are several doing this. Seems a bit dangerous to me.
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Joined: Feb 2006
Posts: 12,129 Likes: 257
Pooh-Bah
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Pooh-Bah
Joined: Feb 2006
Posts: 12,129 Likes: 257 |
Did you mean ivermectin? This is an approved drug for parasites, even in the US. It's very widely used in the Third World where there are some truly horrible parasites that can kill or blind people. It is quite safe, at the dose some people suggest for Covid-19. The only question is does it help or not. You may actually be giving it to your dog. It's the main (or only) ingredient in Heartgard heart worm prevention.
Educating anyone benefits everyone.
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Joined: May 2006
Posts: 5,026 Likes: 98
old hand
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OP
old hand
Joined: May 2006
Posts: 5,026 Likes: 98 |
No this is the Oxford Vaccine that failed in monkeys. They are, as you said, going forward with everything.
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Joined: Feb 2006
Posts: 12,129 Likes: 257
Pooh-Bah
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Pooh-Bah
Joined: Feb 2006
Posts: 12,129 Likes: 257 |
Even though it failed in that species of monkey, it might still work in humans. We are not identical. Hopefully, they tested it in ferrets (which are known to get infected). They would find out in the first trials if humans developed neutralizing antibodies. That would take about a month.
There is an American vaccine that was tested in a different species of monkey, with spectacular results. So even if Oxford fails, there are plenty of good vaccines in trials. Astra Zenica has said they can produce 200 billion doses quickly, so even if it's not the Oxford vaccine, it will be some good one. That manufacturing capacity is not going to sit idle.
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Joined: May 2006
Posts: 5,026 Likes: 98
old hand
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OP
old hand
Joined: May 2006
Posts: 5,026 Likes: 98 |
Last edited by jgw; 06/08/20 08:31 PM.
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Joined: Feb 2006
Posts: 12,129 Likes: 257
Pooh-Bah
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Pooh-Bah
Joined: Feb 2006
Posts: 12,129 Likes: 257 |
I also noticed that Oxford is going to use Brazil as a testing point. Excellent idea. Their government policies make it a pretty sure thing lots of people are going to get exposed. If the vaccine fails to work, they have not done any harm. If it does work, the results would be VERY dramatic. Cheap, too: Just give several thousand people vaccinations, and then see what happens to them.
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Joined: May 2006
Posts: 5,026 Likes: 98
old hand
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OP
old hand
Joined: May 2006
Posts: 5,026 Likes: 98 |
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Joined: Feb 2006
Posts: 12,129 Likes: 257
Pooh-Bah
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Pooh-Bah
Joined: Feb 2006
Posts: 12,129 Likes: 257 |
I think we might have a problem with it getting into the feral cat population. Another reason not to let your pet cat out to come in contact with other cats. Either your cat could get it into the feral cats, or your cat could bring it home to infect you and your family. People feeding the ferals could get infected, even after we vaccinate extensively or reach herd immunity. It can infect other animals, but cats are the ones with the greatest chance to spread it with people.
Educating anyone benefits everyone.
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