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And the process for making monoclonal antibodies is pretty damned scary: They fuse Covid-exposed mouse spleen B-cells with human myeloma cancer cells to make "Frankenstein" hybridoma cells. Those reproduce in a vat and continue making the antibody. As opposed to getting the vaccine, and making your own antibodies.
The antibodies you end up with are mouse antibodies, and they only last about three months. If you were exposed to the SARS-COV2 virus, your T and B cells might get activated but they might not. So you may not end up with any long lasting protection.
Personally, I might not react well since I'm pretty allergic to mice.
The Regeneron MABs are fully humanized to prevent the formation of neutralizing anti-mouse antibodies that were problematic in the early days of treatment with MABs. Mouse allergy shouldn't matter! I only approve of Frankenstein" hybridomas on Halloween
Quote
Regeneron scientists evaluated thousands of fully-human antibodies produced by the company's proprietary VelocImmune® mice, which have been genetically-modified to have a human immune system, as well as antibodies isolated from humans who have recovered from COVID-19. They selected the two most potent, non-competing and virus-neutralizing antibodies and have scaled them up for clinical use with the company's in-house VelociMab® and manufacturing capabilities. The two antibodies bind non-competitively to the critical receptor binding domain (RBD) of the virus's spike protein, which diminishes the ability of mutant viruses to escape treatment, as demonstrated in upcoming Science publications of preclinical research.
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