I think Trump nastiness might make him more popular with his fans, who were going to vote for him anyway. (Assuming they actually can vote. ( EG. felony convictions?) I think it will turn most people who are not Trump fans against him. We shall see.

I am pretty sure Clinton will do her best to portray the moderate candidate, who won't do anything incredibly stupid to destroy the current system. And that's why she will win. Even Conservatives want the current system to stay unchanged. Vote in Trump, Cruz, or Sanders and they have all promised major changes.

In a Trump/Clinton race, I wouldn't be surprised to see a fairly high percentage of Republicans voting for Clinton. Against her current Republican opponents, she IS the Moderate Republican!