Here's an interesting post by a pathologist about the origins of SARS-COV2:

Was SARS-COV2 Natural or Created?

It would help to be a biologist familiar with gene sequences and virus family maps to understand it all, but what it comes down to is a particular gene sequence found in SARS-COV2 that is not found in any of it's close virus relatives and makes it especially infective. He shows several journal papers in which virologists inserted this kind of sequence into viruses for experimental purposes, so it is known technology.

This has nothing to with the silly conspiracy theories about bioweapons. But this is the type of research that the Wuhan lab was doing, in conjunction with American scientists on an NIH grant. It also has little to do with the political blame game, when China and the US are partners at this lab. Lab accidents happen...