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Elimination is probably impossible. Some, including Campbell, are saying Omicron probably came back to humans after bouncing around inside a mouse population for months or years. That seems likely when you look at the origin of Omicron in terms of unique mutations. If not mice, then some other population of animals. Wildlife zoonotic disease programs in this country have vaccinated some skunks and racoons against rabies by dropping vaccine-laced bait. I'm sure vaccinating all the mice in the world would be a lot harder than vaccinating all the people.