If you are interested in an inside story of how the Covid vaccine development was so quick, watch TWIV 858 on YouTube:

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John Mascola joins TWiV to discuss the history and mission of the NIH Vaccine Research Center, how it prepared for devising pandemic vaccines, and development of the COVID-19 vaccines.

They were actually working with Moderna on a Nepa virus vaccine development "drill" to see how fast Moderna could go from gene sequence to vaccine, when the SARS-COV2 RNA sequence was published by the Chinese. (They had already collaborated with Moderna on a Zika vaccine.) So they just plugged the SARS-COV2 sequence into the existing Nepa drill protocol, and had Moderna run with it. The answer was 1 month!

This was with the dual-proline sequence added that fused the spike protein so it could not enter cells through the normal ACE-II receptor. VRC had already figured out how to do that. Essentially, the timing was all perfect. The rest of the time until vaccination launch was all working out mass production, delivery, safety and dosage trials, FDA emergency authorization, etc.

Last edited by pondering_it_all; 01/28/22 06:39 AM.
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